T4 RNA Ligase 2, GMP Grade is an ATP-dependent double-stranded RNA ligase with both intermolecular and intramolecular RNA strand joining activity. Unlike T4 RNA Ligase 1, T4 RNA Ligase 2 exhibits significantly higher ligation activity toward nicked double-stranded RNA than toward single-stranded RNA ends. The ligation reaction requires adjacent 5' phosphate and 3' hydroxyl groups. In addition, this enzyme can ligate the 3' hydroxyl group of RNA to the 5' phosphate group of DNA within RNA/DNA hybrid duplex structures.
       This product is manufactured and quality-controlled in compliance with GMP specifications, ensuring full traceability of the production process and raw materials. The entire production process does not involve the use of antibiotics or any animal-derived materials and excipients. Stringent controls are implemented for process-related impurities including host proteins, exogenous DNA, non-specific endonucleases, DNase, RNase, as well as microbial limits and bacterial endotoxins. This product meets the requirements for raw materials in fields such as vaccine and pharmaceutical production.
 

Store at -20 ± 5℃, Valid for 24 months.  Transport at ≤ 0℃.